Dynamic tests of parathyroid hormone secretion using hemodialysis and calcium infusion cannot be compared
نویسندگان
چکیده
منابع مشابه
serum levels of intact parathyroid hormone, calcium, and phosphorus and risk of mortality in hemodialysis patients
conclusions while high serum pth, calcium, and phosphorus levels could determine the mortality risk in hemodialysis patients, decreased serum phosphorus and pth levels were in association with malnutrition and comorbidities and were not independent risk factors for mortality. background abnormal mineral metabolism is common among hemodialysis patients and has been associated with higher morbidi...
متن کاملParathyroid hormone secretion in low calcium intake smokers.
Dr B. J. Boucher raises the valid issue concerning the association between smoking and the reduction in serum parathyroid hormone (PTH) (Boucher, 2001). With regard to observing this concern in our study (Bonofiglio et al. 2000), it is my pleasure to underscore the following points. First the influence of smoking has been ruled out in girls, since a negligible percentage of them (3) were smoker...
متن کاملAssessment of calcium balance in patients on hemodialysis, based on ionized calcium and parathyroid hormone responses.
BACKGROUND Identification of the underlying causes of secondary hyperparathyroidism (SHPT) in individual patients on hemodialysis (HD) is hampered by the lack of clinically reliable information on calcium balance. The aim of this study was to assess calcium balance during HD sessions with a method that is applicable in day-to-day practice. METHODS Plasma ionized calcium (pCa2+) and parathyroi...
متن کاملCalcium-sensing receptor expression and parathyroid hormone secretion in hyperplastic parathyroid glands from humans.
In uremic patients, severe parathyroid hyperplasia is associated with reduced parathyroid calcium-sensing receptor (CaR) expression. Thus, in these patients, a high serum Ca concentration may be required to inhibit parathyroid hormone (PTH) secretion. This study compares the magnitude of reduction in CaR expression and the degree of the abnormality in Ca-regulated PTH release in vitro. A total ...
متن کاملAntagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats.
Parathyroid hormone (PTH) is an effective bone anabolic agent, but it must be administered parenterally. An orally active anabolic agent would provide a valuable alternative for treating osteoporosis. NPS 2143 is a novel, selective antagonist (a "calcilytic") of the parathyroid cell Ca(2+) receptor. Daily oral administration of NPS 2143 to osteopenic ovariectomized (OVX) rats caused a sustained...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1999
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.1999.00593.x